Alan Thomas

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Alan is involved in numerous clinical studies in dementia with Lewy bodies DLB, including SUPERB, a study supported by the Newcastle BRC.

He is also developing clinical instruments to improve the diagnosis and management of DLB, funded by an NIHR Programme Grant (DIAMOND Lewy).

As Director of Brains for Dementia Research, Alan leads this national programme funded jointly by the Alzheimer’s Society and Alzheimer’s Research UK. He also contributes to several national trials in dementia, such as the MRC Deep and Frequent Phenotyping study, the NIHR HTA trial to improve behavioural disturbance in dementia (SYMBAD) and an NIHR HTA study to improve the management of depression in dementia.

Research Interests

Papers共 403 篇Author StatisticsCo-AuthorSimilar Experts

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Polygenic Risk Discriminates Lewy Body Dementia from Alzheimer's Disease

Anna Mckeever,Peter Swann,Maura Malpetti,Paul C. Donaghy,Alan Thomas,Elijah Mak,Stephen F. Carter, Jerry H. K. Tan,Young T. Hong,Tim D. Fryer,Amanda Heslegrave,Henrik Zetterberg,Li Su,Leonidas Chouliaras,James B. Rowe,John T. O'Brien

ALZHEIMERS & DEMENTIA（2025）

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Distinct Brain Atrophy Progression Subtypes Underlie Phenoconversion in Isolated REM Sleep Behaviour Disorder

Stephen Joza,Aline Delva,Christina Tremblay,Andrew Vo, Marie Filiatrault, Max Tweedale,Jean-François Gagnon,Ronald B Postuma,Alain Dagher,Johannes Klein,Michele Hu,Petr Dusek, Stanislav Marecek,Zsoka Varga,John-Paul Taylor,John T O'Brien,Michael Firbank,Alan Thomas,Paul C Donaghy,Stéphane Lehéricy,Isabelle Arnulf,Marie Vidailhet,Jean-Christophe Corvol, Iceberg Study Group,Richard Camicioli,Howard Chertkow,Simon Lewis,Elie Matar,Kaylena A Ehgoetz Martens, Lachlan Churchill,Michael Sommerauer, Sinah Röttgen,Per Borghammer,Karoline Knudsen,Allan K Hansen,Dario Arnaldi,Beatrice Orso,Pietro Mattioli,Luca Roccatagliata,Oury Monchi,Shady Rahayel

EBioMedicine (2025): 105753-105753

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Molecular Insights into Α-Synuclein Fibrillation: A Raman Spectroscopy and Machine Learning Approach

Nathan P. Coles, Suzan Elsheikh,Agathe Quesnel,Lucy Butler, Claire Jennings, Chaimaa Tarzi,Ojodomo J. Achadu,Meez Islam,Karunakaran Kalesh,Annalisa Occhipinti,Claudio Angione, Jon Marles-Wright,David J. Koss,Alan J. Thomas,Tiago F. Outeiro,Panagiota S. Filippou,Ahmad A. Khundakar

ACS CHEMICAL NEUROSCIENCE (2025)

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Dopaminergic Changes in the Subgenual Cingulate Cortex in Dementia with Lewy Bodies Associates with Presence of Depression

Lina Gliaudelytė,Steven P Rushton,Rolando Berlinguer-Palmini,Alan J Thomas,Christopher M Morris

Translational psychiatryno. 1 (2025): 89-89

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Patterns of Tau, Amyloid and Synuclein Pathology in Ageing, Alzheimer's Disease and Synucleinopathies

Sean J Colloby,Kirsty E McAleese,Lauren Walker,Daniel Erskine,Jon B Toledo,Paul C Donaghy,Ian G McKeith,Alan J Thomas,Johannes Attems,John-Paul Taylor

Brain a journal of neurologyno. 5 (2025): 1562-1576

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Validation of an Algorithm for Detecting Turning in People with Cognitive Impairment, Considering Dementia Disease Subtype

Ríona Mc Ardle, Leigh J. Ryan,Rana Zia Ur Rehman, Emily Dignan, Abbie Thompson,Silvia Del Din,Brook Galna,Alan J Thomas,Lynn Rochester,Lisa Alcock

Gait & Posture (2025): 141-147

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Plasma Biomarkers and Disease Prognosis in Mild Cognitive Impairment with Lewy Bodies

Paul C Donaghy, Jahfer Hasoon, Calum A Hamilton, Joanna Ciafone, Rory Durcan,Nicola Barnett,Kirsty Olsen, Sarah Lawley, Gemma Greenfinch, Michael Firbank,Amanda Heslegrave,Henrik Zetterberg,Louise Allan,John T O'Brien,John-Paul Taylor,Alan J Thomas

Movement disorders official journal of the Movement Disorder Societyno. 6 (2025): 1200-1205

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Outcomes of Patients with Mild Cognitive Impairment with Lewy Bodies or Alzheimer Disease at 3 and 5 Years after Diagnosis

Calum A. Hamilton,Paul C. Donaghy,Rory Durcan,Joanna Ciafone,Kirsty Olsen,Gemma Roberts,Michael J. Firbank,Louise M. Allan,John-Paul Taylor,John T. O'Brien,Alan J. Thomas

NEUROLOGYno. 2 (2024)

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Patterns of Tau, Amyloid and Synuclein Pathology in Ageing, Alzheimer’s Disease and Synucleinopathies

Sean J Colloby,Kirsty E McAleese,Lauren Walker,Daniel Erskine,Jon B Toledo,Paul C Donaghy,Ian G McKeith,Alan J Thomas,Johannes Attems,John-Paul Taylor

Brain (2024)

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Papers共 403 篇Author StatisticsCo-AuthorSimilar Experts