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Bio
Since 1995, Dr. Alistair Barber’s research has focused on the role of retinal neurodegeneration in vision-loss in diabetic retinopathy. This degenerative disease of the retina is a common complication of diabetes and is the leading cause of vision loss in working-age adults in the developed countries. The Barber lab was one of the first to show that diabetes increases retinal cell death by apoptosis, and went on to quantify the accelerated loss of a variety of sub-types of neurons in animal models of diabetes. The lab also identified other morphological changes in neurons, including alterations in the structure of retinal ganglion cell dendrites, and found that these changes are accompanied by deficient expression of synaptic proteins required for neurotransmitter release.
Research Interests
Papers共 173 篇Author StatisticsCo-AuthorSimilar Experts
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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Journal of Extracellular Vesiclesno. 10 (2020): e12373-e12373
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