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Prof. A.G Turhan, MD, PhD is a clinical Hematologist / Oncologist and scientist and a leukemia / hematopoietic stem cell / iPSC expert in Paris Saclay University and Head of Hematology Department at APHP-Paris Saclay Bicetre & Paul Brousse Hospitals. After his Medical School and Internal medicine / Nephrology training in Paris, Dr Turhan undertook and Oncology fellowship in University of British Columbia in Canada, followed by a PhD training in Terry Fox Laboratory under the supervision of C.J. Eaves. After returning to France, he was successively Assistant professor of Haematology, Director of the Cell therapy program in Gustave Roussy Cancer Institute and full professor of Hematology in 2005. Since 2012, he is the Chief of division of Hematology in Paris Saclay University Hospitals where a large number of CML patients are currently being treated with first and second generation TKI therapies.
Prof Turhan is pursuing his research at Inserm U1310 as a Director of the team "Malignant and Therapeutic Stem Cells : Therapeutic Applications". His research Unit has a pioneering expertise in induced pluripotent stem cell (iPSC) technology which represent a major breakthrough in all fields of Medicine and in Onco-Hematology. The Unit has generated > 200 iPSC cell lines from normal and malignant cells in particular in CML as well as from patients with hereditary cancers.
Prof Turhan is a PI Investigator in National Pluripotent Stem Cell Infrastructure INGESTEM (www.ingestem.fr) and in the European RESTORE large scale initiative project (www.restore.com)
The goal of his team is to develop tools based on ESC/ iPSC technologies for both modeling cancer and leukemia and to develop clinically applicable iPSC-derived therapies for cancer, from preclinical phase to Phase I/II. The team has recently shown the possibility of generating cancer organoids in vitro giving rise to the disruptive "cancer in a dish" concept which can be used for drug targeting strategies.
Prof Turhan is a member of American Society of Hematology, AACR, ISSCR and serves as reviewer of Blood, Cancer Research, Oncogene, Leukemia, Experimental Hematology.
Prof Turhan is co-founder of IPSIRIUS, recipient of iLAB award in 2018 (www.ipsirius.com) and Co-Investigator at Center for IPSC Cell Therapy (CITHERA) (www.cithera-ipsc.com)
研究兴趣
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FRONTIERS IN IMMUNOLOGY (2024): 1309010-1309010
Julie Audet,Marc Berger, Johanne Cashman, Yves Chalandon, Laure Coulombel, Stéphane Flamant,Saghi Ghaffari, Sylvain Lefort, François Lemoine,Véronique Maguer-Satta,Franck E. Nicolini, Christian Schmitt,
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Adrien Dufour, Cyril Kurylo,Jan B Stöckl,Denis Laloë, Yoann Bailly, Patrick Manceau, Frédéric Martins,Ali G Turhan, Stéphane Ferchaud, Bertrand Pain, Thomas Fröhlich, Sylvain Foissac,
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Haematologicano. 1 (2024)
STEM CELLSno. 4 (2024): 301-316
Stem cells (Dayton, Ohio)no. 4 (2024): 301-316
Lara Boucher,Nathalie Sorel,Christophe Desterke, Melanie Chollet, Laura Rozalska,Maria Pilar Gallego Hernanz,Emilie Cayssials,Anna Raimbault,Annelise Bennaceur-Griscelli,Ali G. Turhan,Jean-Claude Chomel
Cellsno. 4 (2023): 598-598
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