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个人简介
I am working in the field of oxidative stress-associated disorders since 2009. My main scientific objective is to elucidate the role of redox-sensitive transcription factors during the development but also the progression of pathological conditions such as dysregulated inflammation, rheumatoid arthritis, Alzheimer’s disease, Multiple sclerosis, steatohepatitis, and cancer. In this context, my focus especially lies on the nuclear factor erythroid2-related factor 2 (Nrf2), the main regulator of the intracellular antioxidant response machinery, but also the involvement of nuclear factor 'kappa-light-chain-enhancer' of activated B-cells (NF-κB) and Hypoxia-inducible factor 1-alpha (HIF-1a) are addressed. Experimental setups include cell culture approaches (in vitro), analyses of isolated organs (ex vivo) as well as specific rodent models (in vivo).
研究兴趣
论文共 87 篇作者统计合作学者相似作者
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Maja Charlotte Dittmar,Mersedeh Tohidnezhad,Athanassios Fragoulis, Annette Bücker, Matthias Stein,Thomas Pufe,Yusuke Kubo
Annals of Anatomy - Anatomischer Anzeiger (2024): 152260-152260
Felix Meyer,Annette Bitsch,Henry Jay Forman,Athanassios Fragoulis,Pietro Ghezzi, Bernd Henschenmacher,Rupert Kellner,Jens Kuhne, Tonia Ludwig, Dmitrij Sachno,Gernot Schmid,Katya Tsaioun,
Environment Internationalpp.108940, (2024)
Neoplasia (2023): 100945-100945
International journal of molecular sciencesno. 9 (2023): 7722-7722
Orthopaedic Proceedingsno. SUPP_8 (2023): 3-3
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#Papers: 83
#Citation: 1546
H-Index: 22
G-Index: 38
Sociability: 6
Diversity: 3
Activity: 26
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