基本信息
浏览量:101
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Molecular and cellular bases of development, plasticity and regeneration of neural tissues
The central nervous system presents a daunting complexity and variety of cell types and axonal connections. The laboratory aims at the elucidation of the molecular and cellular bases of the regulatory processes involved in the generation of this system. The Department of Cell Morphology and Molecular Neurobiology is divided in several thematic groups that focus i) on the biology of neural stem cells, radial glia stem cells, motoneuron and glial progenitors and their microenvironment, the stem cell niche during development and under pathological conditions; ii) on neuron-glia interactions and their regulatory influence on axon growth and guidance, as well as synaptogenesis and synaptic plasticity; iii) on the generation of retinal stem cells, their progeny, the generation of retinal progenitors and subpopulations, their integration into neural networks and the possible application to visual system lesions and degeneration. On the molecular level, glycoproteins, chondroitinsulfate proteoglycans and their receptors, tyrosine phosphatases and downstream GTPases of the RhoA-family and GEFs (e.g. Vav-proteins) are topics that are studied using molecular and cell biological tools, and genetically modified animal models.
The central nervous system presents a daunting complexity and variety of cell types and axonal connections. The laboratory aims at the elucidation of the molecular and cellular bases of the regulatory processes involved in the generation of this system. The Department of Cell Morphology and Molecular Neurobiology is divided in several thematic groups that focus i) on the biology of neural stem cells, radial glia stem cells, motoneuron and glial progenitors and their microenvironment, the stem cell niche during development and under pathological conditions; ii) on neuron-glia interactions and their regulatory influence on axon growth and guidance, as well as synaptogenesis and synaptic plasticity; iii) on the generation of retinal stem cells, their progeny, the generation of retinal progenitors and subpopulations, their integration into neural networks and the possible application to visual system lesions and degeneration. On the molecular level, glycoproteins, chondroitinsulfate proteoglycans and their receptors, tyrosine phosphatases and downstream GTPases of the RhoA-family and GEFs (e.g. Vav-proteins) are topics that are studied using molecular and cell biological tools, and genetically modified animal models.
研究兴趣
论文共 331 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
ACS biomaterials science & engineeringno. 5 (2024): 3148-3163
FRONTIERS IN NETWORK PHYSIOLOGY (2023): 1190240-1190240
Jacqueline Reinhard,Cornelius Mueller-Buehl, Susanne Wiemann,Lars Roll, Veronika Luft, Hamed Shabani,Daniel L. Rathbun, Lin Gan,Chao-Chung Kuo, Julia Franzen, Stephanie C. Joachim,Andreas Faissner
Cellular and Molecular Life Sciencesno. 5 (2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn