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个人简介
My main scientific interest is to contribute to an understanding of the complex interactions between human intestinal mucosa and the environment in health and disease. I started in the field by investigating functional effects of positional genetic signals in inflammatory bowel disease. A particular focus is on cellular pathways and networks of NOD-like receptors, autophagy and ER stress. We understand that in intestinal inflammation the human host, together with its associated gut microbiome must be regarded as a functional unit. Disease mechanisms can, therefore, only be described when taking both sides of this “metaorganism” into account. For our questions, we also develop novel tools and techniques using large-scale sequencing and bioinformatics to understand regulatory events and cellular/bacterial response profiles in model systems of chronic inflammatory diseases. I am a member of several large-scale sequencing consortia delineating the genomic and epigenomic architecture of human (inflammatory) diseases.
研究兴趣
论文共 646 篇作者统计合作学者相似作者
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Björn Becker,Felix Wottawa, Mohamed Bakr,Eric Koncina,Lisa Mayr,Julia Kugler, Guang Yang,Samuel J Windross,Laura Neises,Neha Mishra,Danielle Harris,Florian Tran,
iScienceno. 3 (2024): 109173-109173
Archana Bhardwaj,Andreas Münch, Julia Montague,Stefan Koch,Philip Rosenstiel,Celia Escudero-Hernández
United European gastroenterology journal (2024)
Danielle M.M. Harris,Silke Szymczak, Sven Schuchardt, Johannes Labrenz,Florian Tran,Lina Welz,Hanna Graßhoff, Henner Zirpel,Melike Sümbül, Mhmd Oumari, Nils Engelbogen, Ralf Junker,
eBioMedicine (2024): 105056-105056
Florian Tran, Alena Scharmacher, Nathan Baran,Neha Mishra, Marek Wozny, Samuel Pineda Chavez, Archana Bhardwaj, Sophia Hinz,Simonas Juzenas,Joana P. Bernardes,Laura Katharina Sievers,Matthias Lessing,
crossref(2024)
Danielle M.M. Harris,Silke Szymczak, Sven Schuchardt, Johannes Labrenz,Florian Tran,Lina Welz,Hanna Graßhoff, Henner Zirpel,Melike Sümbül, Mhmd Oumari, Nils Engelbogen,Ralf Junker,
EBioMedicine (2024): 105056
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Juan Camilo Castrillon-Betancur, Victor Alonso Lopez-Agudelo, Nina Sommer, Sven Cleeves,Joana Pimenta Bernardes, Saskia Weber-Stiehl,Philip Rosenstiel,Felix Sommer
Antioxidants (Basel, Switzerland)no. 10 (2023): 1889-1889
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Nucleic acids researchno. 14 (2023): 7143-7162
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biorxiv(2023)
Emily Wood,Hinrich Schulenburg,Philip Rosenstiel,Tobias Bergmiller, Dyan Ankrett,Ivana Gudelj,Robert Beardmore
Proceedings of the National Academy of Sciences of the United States of Americano. 40 (2023)
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