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The Fischer Lab studies imprinted genes expressed from their maternal alleles in the endosperm. MET1 DNA methyltransferase methylates and silences imprinted genes. DEMETER antagonizes MET1, allowing maternal alleles to be expressed. DEMETER is a DNA glycosylase and is expressed specifically in the central cell, a maternal gamete fertilized to form the endosperm. We study how DEMETER antagonizes MET1, what restricts DEMETER expression to the central cell, how DEMETER targets imprinted genes, and the identity and function of new imprinted genes.
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论文共 172 篇作者统计合作学者相似作者
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Health & place (2023): 103118
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Frontiers in plant science (2023): 1204279
Research squareno. 1 (2023): 1-15
A. M. Sirunyan,A. Tumasyan,W. Adam, F. Ambrogi, T. Bergauer,J. Brandstetter,M. Dragicevic,J. Ero,A. Escalante Del Valle,M. Flechl, R. Fruehwirth,M. Jeitler,
A. M. Sirunyan,A. Tumasyan,W. Adam, F. Ambrogi,E. Asilar, T. Bergauer,J. Brandstetter, E. Brondolin,M. Dragicevic,J. Eroe, A. Escalante Del Valle,M. Flechl,
European Physical Journal Cno. 4 (2022): 1-15
Proceedings of the National Academy of Sciences of the United States of Americano. 29 (2021)
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