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Skalak was among the first researchers to use engineering principles to understand biological problems. On sabbatical from Columbia in 1967, working in Sweden with P.I. Branemark of the University of Goteborg, he precisely described how red blood cells flow in human tissue, the first study to do so in quantitatively measurable terms. The resulting paper, "Deformation of Red Blood Cells in Capillaries," appeared in the journal Science in 1969.
On his return to Columbia, he undertook a series of studies with Columbia colleague Shu Chien of the properties of red and white blood cells, blood flow, bone and soft tissue growth and how white blood cells move through the body in response to infections. With Branemark, he designed titanium dental implants; his studies of the interaction between titanium and human bone tissue have had wide application in skeletal reconstruction.
On his return to Columbia, he undertook a series of studies with Columbia colleague Shu Chien of the properties of red and white blood cells, blood flow, bone and soft tissue growth and how white blood cells move through the body in response to infections. With Branemark, he designed titanium dental implants; his studies of the interaction between titanium and human bone tissue have had wide application in skeletal reconstruction.
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JSME INTERNATIONAL JOURNAL SERIES C-MECHANICAL SYSTEMS MACHINE ELEMENTS AND MANUFACTURINGno. 3 (1997): 796-803
Biomechanics of Cell Divisionpp.145-159, (1987)
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