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个人简介
My research interests are in the area of free radical biochemistry. Particular interests are centred in the three following fields:
(1) Studying the role of nitric oxide, peroxynitrite and superoxide in the cardiovascular system. Research focuses on the understanding of the endothelial dysfunction mechanisms in obesity, hypertension, and atherosclerosis. We are especially interested in elucidating the role of adipose tissue-derived hormone leptin in vascular tone control. We discovered that chronic hyperleptinemia accompanying obesity could modify the endothelial NO/O2.-/ONOO- metabolism and cause endothelial dysfunction.
(2) Free radical hepatotoxicology. We are interested in the mechanisms of reactive oxidant and nitrogen production in hepatocytes, the biochemistry of biological damage and the consequences of oxidative and nitroso-oxidative stress as well as the mechanisms that liver cells use to attenuate free radical damage. Particular interest is centred on the interaction of cytochrome P450-dependent monooxygenase system of microsomes and reactive nitric oxide species and its role in cell damage by xenobiotics.
(3) Free radical mechanisms of atherosclerosis development. Our research is focused on the mechanisms of low-density lipoproteins (LDL) modification and the prevention of such modification by antioxidants.
(4) Nanotoxicology. Application of nanomaterials in medicine and pharmacy.
(5) Epidemiology, biochemical and immunological diagnosis of Lyme borreliosis and other transmissible tick-borne diseases.
(6) Pathophysiological peculiarities of the recovery period in patients who have contracted COVID-19.
(7) Stem cells of different origin to treat such pathologies as acute respiratory distress syndrome (ARDS), for wound healing etc.
研究兴趣
论文共 17 篇作者统计合作学者相似作者
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Annals of global healthno. 1 (2023): 41-41
Я. Ю. Гапоненко,М. М. Корда
Вісник медичних і біологічних дослідженьpp.5-9, (2023)
Хірургія дитячого вікуpp.17-24, (2023)
International Journal of Medicine and Medical Researchno. 1 (2022): 5-10
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)no. 7 (2021): 705-711
Медична освітаpp.32-37, (2021)
Інфекційні хворобиpp.16-19, (2020)
M. I. Shkilna,M. A. Andreychyn,S. S. Podobivsky,L. Ya. Fedoniuk, V. A. Panychev,O. L. Ivakhiv,N. Yu. Vyshnevska, O. M. Marchuk,M. M. Korda,I. M. Klishch
Bukovinian Medical Heraldno. 1 (93) (2020): 195-201
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作者统计
#Papers: 25
#Citation: 57
H-Index: 3
G-Index: 7
Sociability: 5
Diversity: 0
Activity: 1
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