基本信息
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Bio
以前的工作中,侯照远等首先发现了:1) LIM蛋白Ajuba能特异结合蛋白Snail的是Snail 必需的抑制辅助因子;2) Ajuba通过它的氨基端特异地结合精氨酸甲基转移酶Prmt5,并通过它的羧基端结合Snail进而共同形成一个多蛋白复合体,通过甲基化修饰组蛋白的精氨酸残基来抑制靶基因转录;3) 14-3-3能够结合Snail,并参与调控Snail/Ajuba/Prmt5多蛋白复合体与染色质结合的能力。14-3-3与Snail的结合主要是通过位于羧基端得14-3-3结合位点地关键丝氨酸T179侯照远课题组--基因表达调控实验室的磷酸化。目前已在MCB,Cancer Research, PNAS等期刊发表文章10 多篇。
Research Interests
Papers共 96 篇Author StatisticsCo-AuthorSimilar Experts
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Jie Zhang,Yuanyuan Yu,Xiuqun Zou,Yaning Du, Qiankun Liang,Mengyao Gong, Yurong He, Junqi Luo,Dandan Wu,Xiaoli Jiang,Matt Sinclair,Emad Tajkhorshid,
Nucleic Acids Researchno. 9 (2024): 4969-4984
crossref(2023)
crossref(2023)
openalex(2023)
Clinical pediatricsno. 7 (2023): 99228231201245-962
Chinese Journal of Immunologyno. 7 (2023)
crossref(2023)
Xiuqun Zou,Li Ma,Yihong Zhang,Qun Zhang, Chu Xu,Dan Zhang,Yimin Chu,Jie Zhang,Mengying Li,Hui Zhang,Jiamin Wang, Chicheng Peng,
crossref(2023)
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Author Statistics
#Papers: 103
#Citation: 2661
H-Index: 28
G-Index: 50
Sociability: 6
Diversity: 0
Activity: 1
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