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Bio
陈俐娟教授长期从事天然药物小分子和靶向小分子的药物开发研究,作为项目/课题负责人主持完成40余项国家及省部级科研项目,包括国家863重大项目1项,十一五、十二五及十三五重大新药创制5项,国家自然科学基金仪器重大专项1项、联合基金重点项目1项、面上项目5项。与石药集团、成都金瑞、贵州百灵、成都赜灵生物医药科技有限公司等制药公司签订新药开发横向合作项目10项,项目总经费1亿以上。已培养博士60余名,硕士研究生80余名。相关成果以通讯作者在Nature Communications、Science Advances, Clinical Can. Res、J. Med. Chem.等发表SCI论文250余篇;获授权国际国内专利40余项、多个专利获美国、澳大利亚、日本等国家授权14项。研究团队实现了多个1类新药的临床转化,其中治疗肺癌和脑胶质瘤1类新药“注射用和厚朴酚脂质体”已进入II期临床,治疗血液瘤创新药物“甲磺酸普依司他,即将完成I期临床,治疗骨髓纤维化创新药物“马来酸氟诺替尼片剂”已开展I期临床。
Research Interests
Papers共 442 篇Author StatisticsCo-AuthorSimilar Experts
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Chufeng Zhang, Yulian Chen,Yong Li,Na Shi,Yaxin Teng,Na Li,Minghai Tang,Ziyan Ma,Dexin Deng,Lijuan Chen
European Journal of Medicinal Chemistry (2024): 116076-116076
Weichen Bo, Yangqin Duan,Yurong Zou,Ziyan Ma,Tao Yang,Peng Wang,Tao Guo, Zhiyuan Fu,Jianmin Wang,Linchuan Fan,Jie Liu,Taijin Wang,
Journal of Medicinal Chemistryno. 9 (2024): 7516-7538
Mengshi Hu, Tao Yang,Linyu Yang,Lu Niu,Jinbing Zhu,Ailin Zhao,Mingsong Shi,Xue Yuan, Minghai Tang,Jianhong Yang, Heying Pei,Zhuang Yang,
BLOOD CANCER JOURNALno. 1 (2024)
Journal of Pharmaceutical and Biomedical Analysis (2024): 115984-115984
Chufeng Zhang, Yulian Chen,Yong Li,Na Shi,Yaxin Teng,Na Li,Minghai Tang,Ziyan Ma,Dexin Deng,Lijuan Chen
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024)
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2024)
Yaxin Teng,Rui Wu,Weichen Bo,Minghai Tang,Taijin Wang,Xue Cui,Yong Li,Chufeng Zhang,Ziyan Ma, Zhiyuan Fu, Qing Xu,Jie Liu,
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116240-116240
Bioorganic chemistry (2024): 107569-107569
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Author Statistics
#Papers: 440
#Citation: 12133
H-Index: 61
G-Index: 86
Sociability: 7
Diversity: 1
Activity: 4
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