基本信息
views: 73
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Our research is aimed at understanding virus-host interactions that regulate pathogenesis and outcome of RNA virus infections. Currently, work in the Li laboratory is centered on two main themes. The first one is to dissect innate immunity to infections by positive-strand RNA viruses such as hepatitis C virus and related viruses. We are studying how these viruses are detected by host innate immune sensors such as the Toll-like receptors and RIG-I-like receptors, leading to antiviral and inflammatory responses. The second focus area is to investigate how TRIM56, a tripartite motif protein, contributes to innate antiviral immunity. Studies are ongoing to delineate the molecular determinants by which TRIM56 restricts RNA virus infections and by which it promotes innate immune signaling. To study these themes, we employ virus-cell culture systems and various biochemical, cell biological and molecular approaches.
Research Interests
Papers共 125 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Zhuoyuan Alex Li,Akhilesh Kumar Bajpai, Ruixue Wang, Yaxin Liu,Richard J Webby,Esther Wilk,Weikuan Gu,Klaus Schughart,Kui Li,Lu Lu
Virus research (2024): 199335-199335
Journal of Biological Chemistryno. 5 (2024): 107249-107249
Journal of Immunologyno. 1 (2023): 72.14-72.14
Darong Yang, Yin Wu, Isaac Turan, Joseph Keil,Kui Li,Michael H Chen,Runhua Liu,Lizhong Wang,Xue-Long Sun,Guo-Yun Chen
crossref(2022)
Load More
Author Statistics
#Papers: 125
#Citation: 13403
H-Index: 53
G-Index: 115
Sociability: 6
Diversity: 1
Activity: 0
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn